For SBP, some series have detected that a lesion size of minimum 5 cm, age (e.g., patients aged 40 years and over), spine lesions, RT dose, high M protein levels, existence of light chains, and persistence of M protein after treatment, influence the outcome in these patients and may indicate the presence of higher risks of progression to MM [4, 19, 21, 23, 25, 26, 30, 32–35]. Here, MYOM2 is linked to Miyoshi myopathy.