MYOM2 and hypercalcemia disease: Diagnostic criteria of extramedullary plasmacytoma (EMP) are tissue biopsy-indicating monoclonal plasma cell histology, bone marrow plasma cell infiltration less than 5% of all nucleated cells, absence of osteolytic bone lesions or other tissue involvement without proof of myeloma, hypercalcemia or renal failure, and low-serum M protein concentration, if exists [8, 9].