TG and neoplasm: PDTC was then recognized as a distinct entity, being defined as a thyroglobulin-producing non-follicular non-papillary thyroid carcinoma, disclosing distinctive high grade features (necrosis and mitoses) and a well-developed insular, trabecular or solid pattern of growth present in the majority of the tumour, quite often admixed altogether within the same tumour and less frequently in a “pure” form.