Detailed fine-mapping studies in T1D have since refined the association map to 2 independent groups of SNPs showing strong association with T1D (maximal P=10-28, OR=2.04), the first within IL2Rα intron 1 and the second located 5’ of IL2Rα upstream of neighbouring RBM17 [78]. Here, IL2RA is linked to type 1 diabetes mellitus.