A recent comparison of T1D and MS association at IL2Rα demonstrated substantial discordance; with a T1D risk allele within intron 1 (rs41295061) not associated with MS, a T1D risk allele located 5’ of IL2Rα (rs11594656) conferring protection from MS and a variant conferring risk to both diseases (rs2104286) [81]. The gene discussed is IL2RA; the disease is myeloid sarcoma.