According to the criteria outlined above, the following variables were included in the initial multivariable model: age, gender, time since inclusion, history of coronary artery disease or arterial hypertension, smoking, BMI, chest pain, Hb, creatinine, cephalisation, use of diuretics, ACEI/ARBs or a statin, HR, PaCO2 and PaO2. Here, GSTM1 is linked to Hypertension.