ATP8A2 and glioblastoma: After 5 days of BMPR-IB overexpression or knock-down, the anchorage-independent growth of BMPR-IB-overexpressing glioblastoma cells was drastically inhibited, as shown by a decrease in the number and volume of colonies on soft agar compared with control cells, and the anchorage-independent growth of SF763 cells treated with siBMPR-IB was 2 times as high as that of the si-control-treated cells.