FLVCR1 and infection: Although the widespread cellular distribution of both feTHTR1 and feFLVCR1 in the cat means that FeLV-A and -C are able to infect multiple lineages of haematopoietic cells (lymphoid, erythroid and myeloid), the pathogenic potential of subgroup C viruses appears to be conferred by the ability to interfere with the function of FLVCR1 on erythroid progenitor cells, rather than the widespread infection of diverse cell types [24].