The observed decrease in theexpression of с-myc  under the action of Q12 attests tothe inhibitory effect of this ligand on the transcriptional activity of the Dlx5.The compounds discovered are the first described low-molecular-weight ligands ofDLX5 which can be used for subsequent chemical optimization and the development ofhighly efficient anti-tumor agents. The gene discussed is DLX5; the disease is neoplasm.