TIMP1 and myeloid sarcoma: The genomic typing of 18  allelic groups of the HLA- DRB1  gene and the following single-nucleotide polymorphisms (SNPs) 49A>G of the CTLA4 gene; –509C>T ofthe TGFB1  gene; –590C>T of IL4 gene; –403G>A of the RANTES  gene; –1562C>T of the MMP9  gene; 372C>T of the TIMP1  gene; as well as of the deletion-insertion polymorphism CCR5  (w→d) (“wild type” → deletion of 32  bp), was carried out for Russian MS patients and their healthy parents, followed by the analysis of genetic predisposition to MS using the TDT and AFBAC methods.