It was shown that in adults, the most common malignant tumors of neuroepithelial tissues are associated with the nucleotide excision repair genes XPD, ERCC1 and a gene located in the same (19q13.2-3) region of the chromosome - GLTSCR1 (glioma tumor suppressor candidate of an unknown function) [54]. The gene discussed is ERCC1; the disease is central nervous system cancer.