HLA-DRB1 and malaria: In malaria patients, HLA-DRB1*07 alleles were correlated with improved antibody responses against both domains of the chimeric protein PfCP-2.9 (P. falciparum apical membrane antigen-1, PfAMA-1, and PfMSP-119) but HLA-DRB1*08 had the contrary effect on PfAMA-1 and PfMSP-119[46].