The CD34+ population of circulating cells has been shown to contain EPCs, and a subpopulation of CD34+ cells co-expressing kinase domain receptor (KDR; also known as vascular endothelial growth factor receptor 2 [VEGFR-2]) has been shown to be an independent predictor of cardiovascular events in patients with CAD [9, 10]. The gene discussed is KDR; the disease is coronary artery disorder.