GLRA3 and epilepsy: The availability of large autosomal dominant pedigrees with epilepsy combined with the application of linkage analysis and positional cloning or positional candidate approaches has led to the identification of epilepsy genes that, to date, mostly encode subunits of voltage-gated or ligand-gated ion channels (Mulley et al., 2003; Prasad & Prasad, 2008; Poduri & Lowenstein, 2011).