In previous studies, three SNPs in DGCR8 were associated with OS of ovarian cancer consistent with our result [17], although there is no significant association between the genetic variants in DGCR8 and survival of patients with colorectal cancer [15], head and neck cancer [18] and renal cell carcinoma [16]. The gene discussed is DGCR8; the disease is hereditary clear cell renal cell carcinoma.