However, further analysis of our data indicated that polymorphism of XRCC1 codon 399 and 194 revealed much more significantly increased risk for BCC on sun-exposed area associated with Arg194Trp and Arg194Trp + Trp194Trp (AOR = 3.304, 95 % CI 1.36–8.03 and AOR = 2.643, 95 % CI 1.19–5.89, respectively) (Table 4). This evidence concerns the gene XRCC1 and skin basal cell carcinoma.