Table 3 shows that the risk of CCA increased in the 3rd and 4th highest quartile concentrations of plasma IL-6: OR = 4.55 (95% CI 2.05 to 10.11, P = <0.001) for Quartile 3 and OR = 149.11 (95% CI 40.42 to 550.15, P = <0.001) for Quartile 4. Here, IL6 is linked to cholangiocarcinoma.