CCND1 and B-cell neoplasm: It was first isolated as Parathyroid adenomatosis 1 gene (PRAD1) oncogene clonally rearranged and overexpressed in parathyroid adenomas and is identical to B-cell lymphoma1 gene (bcl-1) protoncogene, which is translocated and overexpressed in a subset of B-cell neoplasms [1].