HTR2C and choroid plexus neoplasm: Lübbert and colleagues cloned in 1987 [91] the mouse 5-HT1C-mRNA (actually 5-HT2C) extracted from choroid plexus tumors; Julius et al. (1988) characterized a cDNA encoding this protein and confirmed the receptor expression in neurons of many regions of central nervous system by in situ hybridization and RNA blot analysis [92].