Assessment of serum levels of HGF revealed statistically significant differences between medians (M) in patients with MM at diagnosis and in remission (M 2001,0 versus 1049,0 pg/mL, P < 0,0001), and in patients with MM in relapse/progression and in remission (M 1370,0 versus 1049,0 pg/mL, P < 0,0001), whereas the difference in HGF levels between patients at the time of diagnosis and in relapse/progression was not statistically significant (P = 0,051), Figure 1. This evidence concerns the gene HGF and Miyoshi myopathy.