Silencing of S100P decreases pancreatic cancer cell growth, motility, invasion, and survival in vitro, whereas S100P overexpression increases pancreatic cancer cell aggressiveness and is associated with increased pancreatic tumor growth and metastasis in vivo (Arumugam et al. 2005; Pajonk et al. 2010). The gene discussed is S100P; the disease is pancreatic neoplasm.