When participants were categorized by the histologic grading system, we observed a significant difference among breast cancer subtypes (P < 0.0001): grade III tumors were more frequent in TN and Her2/neu positive tumors, including luminal B (Her2/neu+) and Her2/neu subtypes (79.3%, 53.7% and 66.3%, respectively). Here, ERBB2 is linked to breast cancer.