Interestingly, increased expression of a number of genes found to be induced by K13 in the BCBL1 cells in the present study, including SOCS1, TNFAIP3, NFKB1A, LTB, IL2RG, RELB, RRAD, CCL5, PHLDA2, CIITA, RGS1 and FAS, have been associated with the plasmablastic phenotype in human lymphomas [68]. This evidence concerns the gene PHLDA2 and lymphoma.