Cytotoxic and apoptotic morphological changes were absent from the normal fibroblasts treated with 10 MOI of Ad.TERT.LacZ over a 7-day period, in contrast to the ovarian cancer-specific apoptosis induced by treatment of cells with 10 MOI of Ad.TERT.Tβ10 over a 10-hour period. The gene discussed is TMSB10; the disease is ovarian cancer.