MAPT and Parkinson disease: A recent meta-analysis of published GWAS was performed by the International Parkinson Disease Genomics Consortium (IPDGC) for a total of 12,386 PD cases and 21,026 controls and suggested that, in addition to SNCA, LRRK2, and MAPT polymorphisms, variants at eight additional loci (HLA-DRB5, BST1, GAK, ACMSD, STK39, MCCC1/LAMP3, SYT11, and CCDC62/HIP1R) are significantly associated with disease risk [25].