ERBB2 and arthritic joint disease: Therefore, if TNJ acts similarly in women and MMTV-neu mice, for women taking the recommended dose of TNJ for other disorders or diseases for which noni has been used (such as wound healing, diabetes, high blood pressure, immune stimulation, arthritis, inflammatory disorders, pain, etc.), its lack of effect on mouse mammary tumor development may suggest that this CAM therapy would not increase a woman's risk of developing HER2+ breast cancer.