Interestingly, Jabaudon et al. [13] reported that sRAGE levels in ALI/ARDS were not influenced by the presence of RAGE-related diseases such as sepsis, diabetes mellitus, end-stage renal disease, coronary artery disease, rheumatoid arthritis, Alzheimer disease, and essential hypertension. The gene discussed is AGER; the disease is early-onset autosomal dominant Alzheimer disease.