EGFR and breast neoplasm: Additionally, β-catenin has been associated with epidermal growth factor receptor (EGFR) family members [12]–[16] and the stability of β-catenin and its TCF/LEF-activating function has been suggested to be regulated via tyrosine phosphorylation by the EGFR family [15], [17]–[19], which may be significant for breast carcinogenesis, since human epidermal growth factor receptor 2 (HER2) is overexpressed in about 30% of human breast tumors [20], [21].