KCNH2 and Bradycardia: From these results we concluded that this method allows detecting of QT prolongation inducers mediated by an HERG blockade (observed as type 2∶1 arrhythmias) but also compounds that affect calcium channels (detected as bradycardia inducers) and sodium channels (detected as bradycardia in the case of the sodium channel blocker Lidocaine or as 2∶1 arrhythmia in the case of the sodium channel activator SDZ-201106).