We then followed the kinetics of the CD8 epitope-specific cells by 2 distinct assays, i.e., in vivo cytotoxicity and ex vivo surface mobilization of CD107a and ICS for IFN-γ and TNF-α, after s.c. parasite infection or i.m. immunization with AdASP-2 vaccine. This evidence concerns the gene CD8A and parasitic infectious disease.