Owing to such proinflammatory properties, IL-32 has been considered to play a key role in the development of various inflammatory diseases, including rheumatoid arthritis (RA), inflammatory bowel disease [5], mycobacterial [6,7] or viral [8-10] infection, chronic obstetric pulmonary disease [11], and pancreatic tumor [12,13]. This evidence concerns the gene IL32 and rheumatoid arthritis.