A few but growing number of immunogenic antigens have been discovered in MM, including idiotypes on MM immunoglobulin, MUC1, WT1, a subgroup of cancer-testis antigens (CTAs), receptor for hyaluronic acid-mediated motility (RHAMM), Dickkopf1 (DKK1) and HM1.24. This evidence concerns the gene HMMR and Miyoshi myopathy.