TREM1 and pancreatitis: Pancreatitis-associated IBD progresses as blood monocytes are recruited and produce proinflammatory cytokines; hence, we think membrane-bound TREM-1 upregulation in the intestine and pancreas is increased on the infiltrating neutrophils in response to the inflammation cascade in process, and these systemic responses may be closely related to organ damage (and MODS).