HP and adenocarcinoma: Since Hp CagA and VacA positive and negative strains were reported to inhibit [24], and in some studies, to promote, the apoptosis in gastric mucosal cells in vivo and in vitro [25–29], we studied the effect of incubation with Hp of human MKN7 adenocarcinoma cell line with relation to expression HSP70, COX-2 and apoptosis.