Constitutive AHR signaling in mouse liver and intestine caused a) an increase in the levels and activity of CD36 (a cell-surface fatty acid receptor and translocase in which the Cd36 gene is a transcriptional target of the AHR); b) inhibition of fatty acid oxidation; and c) an increase in peripheral fat mobilization, hepatic steatosis, and Cyp1a2 RNA levels (Lee et al. 2010). Here, CYP1A2 is linked to fatty liver disease.