SLC1A3 and schizophrenia: GLAST/GLT1 double-knockout (DKO) mice demonstrate multiple brain defects that are similar to schizophrenia-associated developmental defects, including enlarged lateral ventricles; disorganization of neocortex, hippocampus, and olfactory bulb due to impaired neuronal migration; and defective corticothalamic and thalamocortical axonal projections [15].