Engineered bacteriophages fd very effectively elicit specific CTL primary responses to tumor associated antigens (TAAs), as demonstrated by our studies on two HLA-A2 restricted CTL epitopes, MAGE-A3271–279 and MAGE-A10254–262, from tumor associated antigens MAGE-A3 and MAGE-A10. Here, MAGEA3 is linked to neoplasm.