Table 4 gives a summary of the evidence for published POAG genes, with SRBD1, CDKN2B, and TMCO1 giving the most convincing evidence in our larger discovery sample. The best of several significant SNPs within SRBD1 is rs11884064 (p=6.7×10−5), though nearby rs1657855 is marginally more significant (p=2.69×10−5). Here, TMCO1 is linked to open-angle glaucoma.