Stimulation with the citrullinated vimentin 66 to 78 epitope produced much weaker cytokine responses in the current studies - as was observed by Snir and colleagues, who found that HLA-DRB1*0401+ RA patient T cells produced a number of cytokines when incubated with citrullinated vimentin 59 to 78 but not citrullinated vimentin 66 to 78 [7]. Here, HLA-DRB1 is linked to rheumatoid arthritis.