TLR9 and malaria: For example, in a study in Ghana on malaria in pregnancy (n = 304), the TLR9 promoter polymorphism rs187084 C allele was associated with increased risk of low birth weight among term infants [18], while a Brazilian study among adults (n = 304) with mild malaria associated the promoter polymorphisms rs187084 C allele and rs5743836 C allele with high parasitaemia (>10,000 parasite/μl) [19].