HLA-A and nasopharyngeal carcinoma: In the 226 NPC samples with high expression of membranal and cytoplasmic Hsp70, the average HLA-A score was 3.82, which was significantly higher than that (2.81) found in the remaining 281 NPCs with low expression of membranal and cytoplasmic Hsp70 (P < 0.001, independent sample t-test; Figure 4B).