NOXA functions through Bax and/or Bak to induce apoptosis in some cancer cells such as Hela human epithelial cervical cancer cells [9], melanoma cells [11], MCF-7 human breast cancer cells [12], etc. Furthermore, a recent report showed a therapeutic potential of NOXA in treating human breast cancer [12]. The gene discussed is PMAIP1; the disease is cervical carcinoma.