G6PC1 and hepatocellular carcinoma: To find such genes, we developed a novel hormonally-responsive human hepatoma cell line, AH-G6PC, and used it, together with a 4-gene HTG ArrayPlate mRNA assay, to screen the pooled siRNAs comprising a 6650 druggable gene library for their impact on the expression of 2 key GNG regulatory genes, G6PC and PDK4.