ADIPOQ and coronary artery disorder: Interestingly, HMW adiponectin has been shown to serve not only as a predictor of future cardiovascular events in patients with coronary artery disease, but also as a marker for severity of CAD [31], whereas the MMW/HMW ratio, but not LMW or total adiponectin levels, correlated with the incidence of myocardial infarction [32].