The lymph node coefficient (= lymph node metastases/number of removed lymph nodes), which reflects a significant calculated prognostic factor for long-term survival of patients with esophageal adenocarcinoma, also significantly depends on the coexpression of E-cadherin/Eph B3 (P = 0.017) (Table 3). This evidence concerns the gene CDH1 and esophageal adenocarcinoma.