DAPK1 and nasopharyngeal carcinoma: Grifolin, a secondary metabolite isolated from the fresh fruiting bodies of A. confluens, has been shown to inhibit the growth of some cancer cell lines in vitro by up-regulating death-associated protein kinase 1 DAPK1 via p53 in nasopharyngeal carcinoma cells (Luo et al. 2011).