TNFAIP3 and systemic lupus erythematosus: For example, genotyping tag-SNPs at TNFAIP3, one of the autoimmune risk loci, in an African-American SLE cohort revealed a novel African-derived risk haplotype that was in linkage disequilibrium (LD) with a non-synonymous coding SNP [39], whereas in another study [40] re-sequencing of the same region in Europeans and Koreans revealed a deletion of T, followed by a T > A transversion in a non-coding region that showed much stronger odds ratio in Koreans than Europeans for SLE (odds ratio = 2.54 versus 1.7 in Europeans).