We found that the five most significant amino acid positions for psoriasis occurred at 3 positions within HLA-B (residue 97 [p = 1.58×10−53], residue 67 [p = 4.00×10−45], and residue 70 [p = 1.35×10−40]) and 2 positions with HLA-C (residue 156 [p = 3.89×10−51] and residue 97 [p = 4.56×10−45]) (Table S4). Here, HLA-C is linked to psoriasis.