IFNG and neoplasm: This cytokine probably favors tumor growth in steady state conditions by inhibiting the maturation of antigen presenting cells, but at the same time, sustaining their ability for antigen uptake and simultaneously hampering their migration to draining lymph nodes prepares antigen presenting cells to serve as powerful T cell stimulators loaded with TA when the microenvironmental conditions are altered during immune stimulation that could affect a switch of their phenotype by the presence of immune stimulatory cytokines such as IFN-γ and TNF-α that could induce their maturation in situ [49].