Using multiplex bead arrays and ELISAs, we observed that cytokines and chemokines associated with protection against dengue, namely CXCL10 [40], [41], IFN-α [42], [43] and TRAIL [44] are produced by both monocyte subsets in response to dengue virus (Fig. 2 A, B, C). The gene discussed is TNFSF10; the disease is dengue disease.