The dominance of HLA-B in the control of HIV-1 infection is supported by several studies which associated HLA-B*57, B*5801 and B*27 with slower disease progression rates (time to AIDS) and strong virologic (viral load) and immunologic control (CD4 count) [39-48], while B*35, B*5802 and B*18 were associated with ineffective control of viral replication and rapid progression to AIDS [37,43,44,47,49,50]. Here, HLA-B is linked to HIV-1 infection.