Here, we show that S6K1 but not S6K2 is overexpressed in different brain tumours as atypical teratoid tumour, classic medulloblastoma, glioblastoma, and anaplastic oligoastrocytoma compared to normal brain in cancer microarray database; Oncomine (Figure 1). Here, RPS6KB1 is linked to anaplastic oligoastrocytoma.